UV/visible Spectrophotometer in the Development of Biopharmaceuticals
Biopharmaceuticals represent an entirely new generation of human therapeutics. However, due to their inherent complexity, biopharmaceuticals require sensitive, well-established and efficient methods of characterization in order to optimize their safety and efficacy.
In this list, discover how ultraviolet/visible (UV/vis) spectrophotometer rises to the challenges of biopharmaceutical development and manufacturing processes, including:
- Purification
- Determining concentration
- Monitoring intermolecular interactions
UV Vis spectroscopy is also qualitatively useful in some more specialized research. Tracking changes in the wavelength corresponding to the peak absorbance is useful in examining specific structural protein changes and in determining battery composition.Shifts in peak absorbance wavelengths can also be useful in more modern applications such as characterization of very small nanoparticles. The applications of this technique are varied and seemingly endless.